Fibro-adipogenic progenitors prevent skeletal muscle degeneration at acute phase upon tendon rupture in a murine tibialis anterior tenotomy model

Figure 5 The progression of muscle adipogenic degeneration after tendon rupture vs sham surgery in C57BL/6 mice. A: Images of perilipin 1 immunofluorescence staining of the tibialis anterior muscle at 0 day, 1 week, 2 weeks, 4 weeks, and 6 weeks after tibialis anterior tenotomy or sham surgery in C57BL/6 mice; B: The statistical analysis of the area fraction of positive stained area which represents the tendency of adipogenesis (^aP < 0.05, ^bP < 0.05, ^cP < 0.01, ^dP < 0.001, tibialis anterior tenotomy compared to sham surgery side at 1 week, 2 weeks, 4 weeks, and 6 weeks, respectively). TAT: Tibialis anterior tenotomy; SS: Sham surgery.