Human umbilical cord mesenchymal stem cells ameliorate liver metabolism in diabetic rats with metabolic-associated fatty liver disease

Figure 7 Correlation analysis between biochemical indexes and key differential metabolites in rats of each group. A: Spearman correlation heatmap of biochemical indexes and key differential metabolites in the diabetes mellitus (DM) group vs control group comparison. Orange represents positive correlations and blue represents negative correlations; the depth of the color indicates the strength of the correlation; B: Spearman correlation network between biochemical indexes and key differential metabolites in the DM group vs control group comparison. Red lines represent positive correlations and green lines represent negative correlations; the thickness of the lines indicates the strength of the correlation; C: Spearman correlation heatmap of biochemical indexes and key differential metabolites in the DM group vs DM + human umbilical cord mesenchymal stem cells group comparison; D: Spearman correlation network between biochemical indexes and key differential metabolites in the DM group vs DM + human umbilical cord mesenchymal stem cells group comparison. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. Control group, n = 8; diabetes mellitus group, n = 6; diabetes mellitus + human umbilical cord mesenchymal stem cells group, n = 5. FBG: Fasting blood glucose; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TG: Triglyceride.