Comparison between the therapeutic effects of differentiated and undifferentiated Wharton's jelly mesenchymal stem cells in rats with streptozotocin-induced diabetes

Figure 2 Comparison of serum C-peptide concentration and insulin concentration between undifferentiated human Wharton's jelly mesenchymal stem cells and insulin-producing cells in response to glucose stimulation. Differentiated insulin-producing cells (IPCs) secreted significant amounts of C-peptide and insulin, whereas undifferentiated human Wharton's jelly mesenchymal stem cells (MSCs) secreted lower amounts. ^aP < 0.05 when comparing the concentration of C-peptide and insulin by differentiated insulin-producing cells in response to the higher glucose (HG) and lower glucose (LG) environments.