Extracapsular invasion as a risk factor for disease recurrence in colorectal cancer

Table 1 Patients characteristics and clinicopathological features associated with the presence of extracapsular invasion at lymph node metastases

	ECI	Positiven = 16	Negativen = 30	P value
Age (yr)		65.3 ± 16.1	66.5 ± 13.8	0.798
Sex
Male		7	21	0.082
Female		9	9
Location
Colon		13	20	0.295
Rectum		3	10
Histological type
Tub		15	28	0.957
Muc		1	2
pT category
T 1,2		1	10	0.040
T 3,4		15	20
Tumor size (mm)		47.3 ± 15.1	40.4 ± 21.2	0.270
Number of positive LNs		3.63 ± 2.29	1.70 ± 1.27	0.001
Lymphovascular invasion		16	29	0.460
CEA ≥ 3.0		3	3	0.041
Adjuvant treatment	13	0.720	23	0.720

LN: Lymph node; ECI: Extracapsular invasion; CEA: Carcinoembryonic antigen.

Table 2 Patient characteristics and clinicopatholo gical features associated with recurrent disease

	Recurrent disease	Positive	Negative	P value
		8	38
Age (yr)		68.0 ± 17.2	65.7 ± 14.0	0.780
Sex
Male		3	25	0.278
Female		5	13
Location
Colon		6	27	0.795
Rectum		2	11
Histological type
Tub		7	36	0.451
Muc		1	2
PT category
T 1, 2		0	11	< 0.001
T 3, 4		8	27
Tumor size (mm)		44.9 ± 11.6	42.5 ± 20.8	0.679
Number of positive LNs		2.38 ± 1.41	2.37 ± 2.02	0.906
ECI		6	10	0.009
Lymphovascular invasion		8	37	0.643
CEA	≥ 3.0	3	3	0.093
Adjuvant treatment		5	31	0.473

ECI: Extracapsular invasion; CEA: Carcinoembryonic antigen.