Effect of 5-Aza-2’-deoxycytidine on immune-associated proteins in exosomes from hepatoma

Table 1 Immune-related molecules of exosomes in control and experimental groups (mean ± SD)

	n	HepG2		P	Hep3B		P
		Control group	Experiment group		Control group	Experiment group
HSP70	3	74.2 ± 3.1	99.8 ± 5.2	< 0.01	70.2 ± 5.1	99.9 ± 3.8	< 0.01
HLA-I	3	53.3 ± 2.5	79.6 ± 6.1	< 0.01	40.6 ± 2.7	86.7 ± 3.6	< 0.01
NY-ESO-1	3	38.2 ± 4.2	58.2 ± 4.3	< 0.01	32.1 ± 4.6	70.3 ± 2.9	< 0.01

Table 2 Exosomes and their total protein level in hepatoma cells (mean ± SD)

Subject	n	HepG2 con	HepG2 exp	P	Hep3B con	Hep3B exp	P
Exo No	3	3.56 × 108± 2.6 × 102	4.53 × 109± 3.7 × 102	0.010	3.12 × 108± 6.2 × 102	4.13 × 109± 3.7 × 102	0.021
Exo Pro	3	0.92 ± 0.13 mg	1.31 ± 0.16 mg	0.012	0.89 ± 0.10 mg	1.52 ± 0.16 mg	0.011

Exo: Exosome; con: Control group; exp: Experiment group.