Effect of vanadium on colonic aberrant crypt foci induced in rats by 1,2 Dimethyl hydrazine

Table 2 Chemopreventive efficacy of 0.5-ppm vanadium (supplemented ad libitum through drinking water) on the incidence and multiplicity of DMH induced rat colonic tumors

Group	Number of rats		Colon tumor incidence (percentage of tumor bearing rats)	Total number of tumors			Colon tumor multiplicity (mean tumor/animal, Mean ± SD)
	Total	Total Tumor counts		Adenoma	Carcinoma	All neoplasia	Adenoma	Carcinoma	All neoplasia
A	10	-	-	-	-	-	-	-	-
B	10	10	100	97	64	120	9.7 ± 0.3	6.4 ± 0.1	12 ± 0.1
C	10	06	60a	23	16	31	2.3 ± 0.2	1.6 ± 0.2	3.1 ± 0.1b
D	10	-	-	-	-	-	-	-	-

^aP < 0.01 vs DMH-only group B by Fischer’s exact probability test;

^bP < 0.05 vs Group B by Student’s t-test.