Difference of gene expression profiles between esophageal carcinoma and its pericancerous epithelium by gene chip

Table 2 Genes with expression difference > 3 or < 0.33 on average ratio between esophageal carcinoma and normal epithelium

Genbank-ID	Fcf	Gene name	R1	R2	AR
hsu67963		Human lysophospholipase homolog(HU-K5)mRNA, complete cds.	0.11	0.16	0.14
Hslimdp	8	H.sapiens mRNA for ZNF185 gene.	0.15	0.23	0.19
4505166			0.13	0.26	0.19
d87451	15	Human mRNA for KIAA0262gene,complete cds	0.13	0.31	0.22
hsy15409	11	Homo sapiens mRNA for putative glucose 6-phosphate translocase.	0.28	0.23	0.25
hsu16996	12	Human protein tyrosine phosphatase mRNA, complete cds.	0.31	0.26	0.29
hsu30255	12	Human phosphogluconate dehydrogenase (hPGDH) gene, complete cds.	0.29	0.30	0.29
4504714			0.47	0.16	0.31
ab002349	15	Human mRNA for KIAA0351 gene, complete cds.	0.14	0.50	0.32
humpai2	13	Human placental plasminogen activator inhibitor mRNA, complete cds.	0.28	0.35	0.32
hsu73824		Human p97 mRNA, complete cds.	0.30	0.34	0.32
hsa132270	2	Homo sapiens mRNA for integral type I protein p24B (p26).	0.31	0.34	0.33
Humorfkg1f	11	Human mRNA for KIAA0058 gene,complete cds.	0.31	0.36	0.33
s74452	3	Cyclin B1{promoter region}[human,cervical carcinoma cell line, HeLa cells,Genomic, 351 nt].	3.21	2.79	3.00
hspros27	10	H.sapiens PROS-27 mRNA.	3.29	2.85	3.07
Hstrr	10	Human mRNA for transferrin receptor.	2.70	3.48	3.09
Humprion	15	Homo sapiens mRNA for prion protein, complete cds.	3.07	3.19	3.13
hshr21spa	13	H.sapiens mRNA for protein involved in DNA double-strand break repair.	2.29	4.01	3.15
AB00109S14	11	Homo sapiens gene for H-cadherin, exon 14 and complete cds.	2.95	3.50	3.23
hsranbp1	11	H.sapiens mRNA for RanBP1.	3.98	2.57	3.27
Hsxprf	8	Homo sapiens mRNA for putative transcription factor XPRF.	3.35	3.38	3.37
humcd3621	11	Human antigen CD36 (clone 21) mRNA, complete cds.	3.28	3.54	3.41
Humsparc	5	Human SPARC/osteonectin mRNA, complete cds.	2.87	3.96	3.42
Humhcamap3	5	Human gene for hepatitis C-associated microtubular aggregate protein p44, exon 4.	3.72	3.30	3.51
Humprofii	5	Human profilin II mRNA, complete cds.	3.07	4.07	3.57
5729755			2.35	4.88	3.61
Hsrnasmg	13	H.sapiens mRNA for Sm protein G.	2.91	4.57	3.74
Humpgc	5	Human chondroitin sulfate proteoglycan core protein mRNA, 3' end.	3.67	3.91	3.79
hstop2a10	8	Homo sapiens topoisomerase II alpha (TOP2A) gene,exons 34 and 35,and complete cds.	4.02	3.76	3.89
hsu09559	14	Human Rch1 (RCH1) mRNA, complete cds.	3.75	4.03	3.89
humcol1a42		Human alpha-1 collagen type IV gene, exon 52.	4.37	3.69	4.03
hsinta6r	11	Human mRNA for integrin alpha 6.	3.28	5.43	4.35
d86983	15	Human mRNA for KIAA0230 gene, partial cds.	4.71	4.84	4.78
hsu26555		Human versican V2 core protein precursor splice-variant mRNA, complete cds.	6.93	5.91	6.42
hspgp95	13	Human mRNA for protein gene product (PGP) 9.5.	5.66	7.54	6.60
af052124	15	Homo sapiens clone 23810 osteopontin mRNA, complete cds.	11.77	4.63	8.20
Humcolva		Human alpha-2 type V collagen gene, 3' end.	7.64	10.17	8.91
humca1xia	15	Human alpha-1 type XI collagen (COL11A1) mRNA, complete cds.	6.75	12.07	9.41
Hscalbr11		Human mRNA for 27-kDa calbindin.	6.72	12.17	9.45
hsu50078	8	Human guanine nucleotide exchange factor p532 mRNA, complete cds.	12.28	17.11	14.70
Hsop	5	Human mRNA for osteopontin.	20.23	20.22	20.23

Fcf: function classification average ratio > 3: up regulation average ratio < 0.33: down regulation; R1: the first ratio; R2: the second ratio; AR: R1 + R2 average ratio.