Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer

doi:10.3748/wjg.v9.i10.2261

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Oct 15, 2003 (publication date) through May 1, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 2003; 9(10): 2261-2265
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2261

Table 4 Duodenal mucosal EGF content in sham operation and duodenal ulcer rats with or without oral EGF¹

Group	Sham operation		Duodenal ulcer
Group	-EGF	+EGF	-EGF	+EGF
	Duodenal mucosal EGF (ng/g mucosa)
Day 5	35.7 ± 12.9^ab	76.0 ± 13.7^c	28.3 ± 9.2^a	68.3 ± 10.9^bc
Day 15	84.8 ± 22.8^a†	47.5 ± 19.3^ab	12.9 ± 3.9^b*	28.3 ± 10.5^b†

¹Data are mean ± SE (n = 6). Values in a row not sharing a su-perscript letter were significantly different (P < 0.05) by Fisher’s least significant difference test. ^*The content of EGF in duode-nal mucosa was significantly different (P < 0.05) from that in the control group (61.1 ± 5.4 ng/g mucosa, n = 6) on day 0 by Dunnett’s test. ^†P < 0.05 compared with day 5 within the same group by Fisher’s least significant difference test.

Citation: Chao JC, Liu KY, Chen SH, Fang CL, Tsao CW. Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer. World J Gastroenterol 2003; 9(10): 2261-2265
URL: https://www.wjgnet.com/1007-9327/full/v9/i10/2261.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i10.2261