Stress kinase inhibition modulates acute experimental pancreatitis

Figure 4 SB203580 treatment leads to necrosis development during cerulein pancreatitis. Animals were treated as in Figure 3. Pancreata were then removed and tissue sections HE stained for light microscopy. untreated control, cerulein alone, 30 mg/kg CEP1347 4 h prior to cerulein, 30 mg/kg CEP1347 and SB203580 prior to cerulein, and 30 mg/kg SB203580 prior to cerulein. Original magnification 50 fold (A-E). Panel F shows a higher (150-fold) magnification of panel E.