Diagnostic approach to patients with cholestatic jaundice

Table 4 Causes and syndromes of ductopenia in the adult patient

Syndromatic ductopenia (Alagille syndrome)

Non-syndromatic adult ductopenia

Ductal plate malformation (congenital hepatic fibrosis, biliary atresia

Primary biliary cirrhosis, autoimmune cholangitis

Primary sclerosing cholangitis

Chronic rejection

Graft-versus-host disease

Sarcoidosis

Cystic fibrosis

Byler disease (progressive familial intrahepatic cholestasis)

Histiocytosis X and

Different drugs (amoxicillin-clavulanic acid, carbamazepine)

Duct destruction after regional chemotherapy (e.g. floxuridine)

Idiopathic adulthood ductopenia