Experimental research on phospholipids variation of halothane on liver mitochondria

Table 1 The variation of phospholipid in liver mitochondrial membrane affected by halothane and sevoflurane (phospholipid unit: × 10⁹ peak area/g mitochondrial albumin ^-x±s)

Group	PE	PI	PS	CL	PC	SPH	LPC
Control	1.48 ± 0.26	1.16 ± 0.19	0.84 ± 0.09	1.02 ± 0.11	2.93 ± 0.28	3.98 ± 0.59	4.54 ± 0.42
At low concentration
Sevoflurane	1.37 ± 0.19	1.08 ± 0.09	0.78 ± 0.07	0.95 ± 0.11	2.72 ± 0.17	3.76 ± 0.33	4.89 ± 0.33
	(-7.62%)	(-7.12%)	(-6.93%)	(-6.55%)	(-7.19%)	(-5.52%)	(+7.81%)
Halothane	1.19 ± 0.12	0.96 ± 0.06	0.70 ± 0.80	0.85 ± 0.16	2.50 ± 0.26	3.37 ± 0.29	5.90 ± 0.12
	(19.60%)ab	(-17.24%)ab	(-16.94%)ab	(-16.25%)	(-14.38%)ab	(15.43%)ab	(+30.1%)ab
At high concentration
Sevoflurane	1.30 ± 0.12a	1.02 ± 0.04a	0.63 ± 0.04a	0.89 ± 0.70a	0.64 ± 0.16a	3.57 ± 0.22a	5.69 ± 0.32c
	(11.89%)	(12.02%)	(-11.26%)	(-12.55%)	(-10.36%)	(-10.40%)	(+25.35%)
Halothane	1.06 ± 0.09c	0.81 ± 0.07c	0.78 ± 0.09c	0.75 ± 0.09c	2.09 ± 0.16c	2.95 ± 0.24c	7.81 ± 0.67c
	(-28.38%)b	(-2.41%)b	(-25.24%)b	(-26.59%)b	(-2867%)b	(-26.61%)b	(+41.87%)b

^aP < 0.05,

^cP < 0.01 vs control;

^bP < 0.05 vs sevoflurane.