Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice

Figure 3 Helicobacter pylori IgG and IgM antibodies in mice sera. A: A model of vaginal infection; B: A model of gastric infection. V1: Vagina infected with Candida J115; V2: Vagina infected with Candida H100; V3: Vagina infected with Candida Ca-co-Hp; VC: Vagina infected with Candida Ca10231; VN: Vagina treated with saline solution. G1: Mice with gastric infection with Helicobacter pylori (H. pylori) and vagina infected with Candida Ca10231; G2: Mice infected with Candida W49; G3: Mice infected with Candida F67; G4: Mice infected with Candida Ca-co-Hp; GC: Mice infected with Ca10231; GN: Gavage saline solution. Candida strains J115, H100, W49, F67, and Ca-co-Hp were positive for H. pylori 16S rDNA and ureA genes. The control Candida Ca10231 strain was negative for H. pylori 16S rDNA and ureA genes. Results are presented as the mean ± SD (n = 4), with P values calculated using ANOVA. Different letters denote significant differences.