Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice

doi:10.3748/wjg.v32.i7.115143

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2026; 32(7): 115143
Published online Feb 21, 2026. doi: 10.3748/wjg.v32.i7.115143

Table 7 Rates of positive detection for Helicobacter pylori 16S rDNA or urease A genes in the placenta and fetal membranes of cesarean section-delivered offspring mice, n (%)

Group		Number of examined samples	Placenta		Fetal membranes
Group		Number of examined samples	*Hp 16S rDNA* positive samples**	*Hp ureA* positive samples**	*Hp 16S rDNA* positive samples**	*Hp ureA* positive samples**
Modeling of vaginal infection with Candida	V1	4	1 (25.0)	0 (0)	1 (25.0)	0 (0)
	V2	6	2 (33.3)	1 (16.7)	1 (16.7)	1 (16.7)
	V3	6	2 (33.3)	0 (0)	1 (16.7)	2 (33.3)
	VC	4	0 (0)	0 (0)	0 (0)	0 (0)
	VN	4	0 (0)	0 (0)	0 (0)	0 (0)
Modeling of gastric infection with Candida	G1	4	0 (0)	1 (25.0)	0 (0)	1 (25.0)
	G2	4	0 (0)	0 (0)	0 (0)	0 (0)
	G3	4	1 (25.0)	1 (25.0)	0 (0)	1 (25.0)
	G4	4	0 (0)	0 (0)	0 (0)	0 (0)
	GC	4	0 (0)	0 (0)	0 (0)	0 (0)
	GN	4	0 (0)	0 (0)	0 (0)	0 (0)

Hp: Helicobacter pylori; ureA: Urease A.

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Citation: Xu XL, Luo TT, Liu Q, Cui GZ, Wu DY, Wu XJ, Yang TX, Sun JC, Jian HF, Zhuo SW, Chen ZH. Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice. World J Gastroenterol 2026; 32(7): 115143
URL: https://www.wjgnet.com/1007-9327/full/v32/i7/115143.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i7.115143

Xu XL, Luo TT, Liu Q, Cui GZ, Wu DY, Wu XJ, Yang TX, Sun JC, Jian HF, Zhuo SW, Chen ZH. Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice. World J Gastroenterol 2026; 32(7): 115143 [PMID: 41694489 DOI: 10.3748/wjg.v32.i7.115143]

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