Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice

Table 5 Rates of positive detection for the Helicobacter pylori 16S rDNA or urease A genes in offspring mice, n (%)

Group		Number of examined mice	Gastric mucosa samples1		Intestinal tissues1		Number of examined mice	Gastric mucosa samples2		Intestinal contents2		Number of examined mice	Gastric mucosa samples3		Intestinal contents3
			Hp 16S rDNA positive samples	Hp ureA positive samples	Hp 16S rDNA positive samples	Hp ureA positive samples		Hp 16S rDNA positive samples	Hp ureA positive samples	Hp 16S rDNA positive samples	Hp ureA positive samples		Hp 16S rDNA positive samples	Hp ureA positive samples	Hp 16S rDNA positive samples	Hp ureA positive samples
Modeling of vaginal infection with Candida	V1	8	3 (37.5)	1 (12.5)	5 (62.5)	3 (37.5)	15	0 (0)	0 (0)	1 (6.7)	0 (0)	16	2 (12.5)	1 (6.3)	0 (0)	2 (12.5)
	V2	10	3 (30.0)	2 (20.0)	3 (30.0)	0 (0)	16	2 (12.5)	0 (0)	0 (0)	0 (0)	17	2 (11.8)	0 (0)	1 (5.9)	0 (0)
	V3	10	3 (30.0)	0 (0)	0 (0)	1 (10.0)	17	6 (35.3)	0 (0)	3 (17.6)	3 (17.6)	18	2 (11.1)	0 (0)	2 (11.1)	0 (0)
	VC	6	0 (0)	0 (0)	0 (0)	0 (0)	8	0 (0)	0 (0)	0 (0)	0 (0)	9	0 (0)	0 (0)	0 (0)	0 (0)
	VN	8	0 (0)	0 (0)	0 (0)	0 (0)	15	0 (0)	0 (0)	0 (0)	0 (0)	14	0 (0)	0 (0)	0 (0)	0 (0)
Modeling of gastric infection with Candida	G1	8	0 (0)	2 (25.0)	0 (0)	1 (12.5)	14	0 (0)	4 (28.6)	1 (7.1)	0 (0)	11	3 (27.3)	2 (18.2)	2 (18.2)	0 (0)
	G2	8	1 (12.5)	1 (12.5)	1 (12.5)	1 (12.5)	18	1 (5.6)	2 (11.1)	3 (16.7)	0 (0)	14	3 (21.4)	4 (28.6)	1 (7.1)	0 (0)
	G3	8	1 (12.5)	1 (12.5)	2 (25.0)	2 (25.0)	20	1 (5.0)	3 (15.0)	4 (20.0)	0 (0)	19	3 (15.8)	0 (0)	2 (10.5)	0 (0)
	G4	8	0 (0)	3 (37.5)	0 (0)	0 (0)	14	0 (0)	0 (0)	5 (35.7)	0 (0)	10	1 (10.0)	0 (0)	3 (30.0)	1 (10.0)
	GC	7	0 (0)	0 (0)	0 (0)	0 (0)	20	0 (0)	0 (0)	0 (0)	0 (0)	12	0 (0)	0 (0)	0 (0)	0 (0)
	GN	8	0 (0)	0 (0)	0 (0)	0 (0)	12	0 (0)	0 (0)	0 (0)	0 (0)	10	0 (0)	0 (0)	0 (0)	0 (0)

¹0-week mice.

²3-week mice.

³6-week mice.

Hp: Helicobacter pylori; ureA: Urease A.