Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. Feb 21, 2026; 32(7): 115143
Published online Feb 21, 2026. doi: 10.3748/wjg.v32.i7.115143

Table 2 Grouping of mice models

Models	Groups	Groups number	Strains for modeling
Model of vaginal infection caused by Candida	Experimental group	V1 (n = 10)	J115
		V2 (n = 10)	H100
		V3 (n = 10)	Ca-co-Hp
	Control group	VC (n = 8)	Ca10231
	Normal group	VN¹ (n = 8)
Model of gastric infection with Candida	Experimental group	G1² (n = 10)	Helicobacter pylori and Ca10231
		G2 (n = 10)	W49
		G3 (n = 10)	F67
		G4 (n = 10)	Ca-co-Hp
	Control group	GC (n = 8)	Ca10231
	Normal group	GN³ (n = 8)

¹VN group mice were inoculated intravaginally with saline solution.

²G1 group mice were simultaneously infected with Helicobacter pylori via gavage and Ca10231 via vaginal instillation.

³GN group mice received saline solution via gavage.

Citation: Xu XL, Luo TT, Liu Q, Cui GZ, Wu DY, Wu XJ, Yang TX, Sun JC, Jian HF, Zhuo SW, Chen ZH. Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice. World J Gastroenterol 2026; 32(7): 115143
URL: https://www.wjgnet.com/1007-9327/full/v32/i7/115143.htm
DOI: https://dx.doi.org/10.3748/wjg.v32.i7.115143

Xu XL, Luo TT, Liu Q, Cui GZ, Wu DY, Wu XJ, Yang TX, Sun JC, Jian HF, Zhuo SW, Chen ZH. Candida-mediated vertical transmission of Helicobacter pylori in C57BL/6J mice. World J Gastroenterol 2026; 32(7): 115143 [PMID: 41694489 DOI: 10.3748/wjg.v32.i7.115143]

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