Prognostic value of postoperative CEA/CA19-9 positivity and elevation relative to preoperative levels in gastric cancer

Table 6 Univariate and multivariate logistic regression analyses for postoperative carbohydrate antigen 19-9 elevation

Variables	Univariate analysis		Multivariable analysis
	OR (95%CI)	P value	OR (95%CI)	P value
N stage
N0, N1	Reference		Reference
N2	1.651 (1.084-2.516)	0.019	1.489 (0.968-2.291)	0.07
N3	3.251 (2.151-4.915)	< 0.001	2.344 (1.490-3.686)	< 0.001
Differentiation
Moderate, good	Reference		Reference
Poor	1.528 (1.088-2.145)	0.014	1.245 (0.857-1.808)	0.250
Vascular invasion
Negative	Reference		Reference
Positive	1.863 (1.280-2.711)	0.001	1.414 (0.945-2.116)	0.092
Post-CEA
Negative	Reference		Reference
Positive	3.628 (2.026-6.496)	< 0.001	2.559 (1.380-4.746)	0.003
Post-CA19-9
Negative	Reference		Reference
Positive	2.543 (1.286-5.029)	0.007	1.301 (0.613-2.760)	0.493
LMR
≥ 4.32	Reference		Reference
< 4.32	1.529 (1.091-2.143)	0.014	1.442 (1.009-2.062)	0.044

CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; OR: Odds ratio; CI: Confidence interval; LMR: Lymphocyte to monocyte ratio.