Wenyang Jiedu Huayu Formula targets succinate metabolism to alleviate acute-on-chronic liver failure

doi:10.3748/wjg.121244

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 7, 2026; 32(37): 121244
Published online Oct 7, 2026. doi: 10.3748/wjg.121244

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Figure 5 Wenyang Jiedu Huayu Formula improves mitochondrial ultrastructure in acute-on-chronic liver failure rats. A: Representative transmission electron microscopy images of mitochondria in hepatocytes from each group. Scale bars: 1 μm (× 12000) and 500 nm (× 30000). Green arrows: Normal mitochondria; orange arrows: Damaged mitochondria; yellow arrows: Mitophagic structures; B: Semi-quantitative assessment of mitochondrial damage using the Flameng scoring system. Data are presented as mean ± SD. ^dP < 0.0001. NC: Normal control group; WYJD: Wenyang Jiedu Huayu Formula; WYIN: Wenyang Jiedu Huayu Formula plus dimethyl malonate.

Citation: Zhou J, Tian XL, Zhou YF, Zhou ZY, Tan NH, Chen B. Wenyang Jiedu Huayu Formula targets succinate metabolism to alleviate acute-on-chronic liver failure. World J Gastroenterol 2026; 32(37): 121244
URL: https://www.wjgnet.com/1007-9327/full/v32/i37/121244.htm
DOI: https://dx.doi.org/10.3748/wjg.121244

Zhou J, Tian XL, Zhou YF, Zhou ZY, Tan NH, Chen B. Wenyang Jiedu Huayu Formula targets succinate metabolism to alleviate acute-on-chronic liver failure. World J Gastroenterol 2026; 32(37): 121244 [DOI: 10.3748/wjg.121244]

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