Wenyang Jiedu Huayu Formula targets succinate metabolism to alleviate acute-on-chronic liver failure

doi:10.3748/wjg.121244

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World Journal of Gastroenterology

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1007-9327

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Oct 7, 2026; 32(37): 121244
Published online Oct 7, 2026. doi: 10.3748/wjg.121244

Table 2 Flameng scoring criteria for mitochondrial damage

Score	Description
0	Normal mitochondrial morphology
1	Mild swelling, decreased matrix density, and separated cristae
2	Moderate swelling, translucent matrix, and intact cristae
3	Severe swelling, condensed matrix, and ruptured cristae
4	Severe swelling with ruptured cristae, complete loss of inner and outer membranes, and vacuolation

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Citation: Zhou J, Tian XL, Zhou YF, Zhou ZY, Tan NH, Chen B. Wenyang Jiedu Huayu Formula targets succinate metabolism to alleviate acute-on-chronic liver failure. World J Gastroenterol 2026; 32(37): 121244
URL: https://www.wjgnet.com/1007-9327/full/v32/i37/121244.htm
DOI: https://dx.doi.org/10.3748/wjg.121244

Zhou J, Tian XL, Zhou YF, Zhou ZY, Tan NH, Chen B. Wenyang Jiedu Huayu Formula targets succinate metabolism to alleviate acute-on-chronic liver failure. World J Gastroenterol 2026; 32(37): 121244 [DOI: 10.3748/wjg.121244]

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