Salidroside mitigates experimental colitis through cyclic adenosine monophosphate pathway activation and suppression of enteric glial cell responses

Figure 2 Salidroside attenuated colonic injury in dextran sulfate sodium salt-induced colitis mice. A: Results of hematoxylin-eosin staining of mouse: Control group (A1); Dextran sulfate sodium salt (DSS) group (A2); DSS + salidroside (Sal) group (A3); The magnified images show the corresponding black rectangle areas in greater detail (A4-A6); B: Results of alcian blue-periodic acid Schiff staining of mouse: Control group (B1); DSS group (B2); DSS + Sal group (B3); The magnified images show the corresponding black rectangle areas in greater detail (B4-B6); C: Histological index scores; D: The number of goblet cells in each crypt. Data are shown as mean ± SEM (n = 8), P values were calculated using one-way analysis of variance with Tukey’s test for Figure 2C and D. ^bP < 0.01. DSS: Dextran sulfate sodium salt; Sal: Salidroside.