Clinical efficacy and mechanism of Bletilla striata and Chinese herbal compounds in treatment of peptic ulcer

Table 3 Clinical efficacy of Bletilla striata compound formulations

Ref.	Study focus	Herbal formula composition	Control group treatment	Research findings
Zhao et al[21]	Huoxue Yuyang Granule in treating gastric ulcers with stomach collateral blood stasis pattern	Bletilla striata, Dendrobium, Gynostemma pentaphyllum, Pseudostellaria heterophylla, Aucklandia lappa, Sepia esculenta, Corydalis yanhusuo, Gallus gallus domesticus, etc.	Ranitidine, hydrotalcite tablets	The treatment group exhibited significantly higher complete healing and total effectiveness rates than the control group, along with notable improvements in multiple clinical symptoms
Liu[22]	Treatment of peptic ulcers using Pseudo-ginseng Rhizoma Bletillae Powder combined with quadruple therapy	Bletilla striata, Panax notoginseng	Standard Western quadruple therapy	The integrated Chinese-Western treatment group achieved a higher total effectiveness rate, along with faster symptom resolution and ulcer healing, compared to the control group
Qin and Deng[23]	Treatment of peptic ulcer with Zhuang Yao Yuyang San	Ilex rotunda, Panax notoginseng, Taraxacum mongolicum, Bletilla striata, Astragalus membranaceus, Sepia esculenta, etc.	Omeprazole capsules, clarithromycin tablets, metronidazole tablets	The treatment group demonstrated a higher Helicobacter pylori eradication rate compared to the control group, with comparable ulcer healing efficacy
Li et al[24]	Use of Shugan Yuyang Decoction in managing gastric ulcers	Bletilla striata, stir-fried Bupleurum chinense, Paeonia lactiflora, Trogopterus dung, stir-fried Aurantii Fructus Immaturus, Angelica sinensis, etc.	Conventional Western medicine	The observation group showed a significantly higher overall effectiveness rate than the control group
Chen et al[25]	Clinical efficacy of traditional Chinese medicine for Helicobacter pylori-positive peptic ulcers	Bletilla striata, Bupleurum chinense, Paeonia lactiflora, Citrus reticulata, Pinellia ternata, Pseudostellaria heterophylla, Poria cocos, etc.	Anti-H. pylori agents and other conventional Western treatments	Bletilla striata forms a protective film over ulcers, reduces mucosal inflammation, improves microcirculation, accelerates mucosal repair, and promotes ulcer healing