Whole-exome sequencing identifies new pathogenic germline variants in patients with colorectal polyposis

Table 1 Characterization and clinical-pathological assessment of participants of study

Gender	n (%)
Male	14 (48.1)
Female	13 (51.9)
Age of polyposis diagnosis	Mean (minimum-maximum)
	51 (19-69)
Polyposis type
Classic polyposis	2 (7.4)
Attenuated polyposis	25 (92.6)
Age of first diagnosed tumor	Mean (minimum-maximum)
	51 (19-64)
Primary diagnosed tumor site1
Colorectal	13 (76.4)
Endometrium	1 (5.9)
Breast	1 (5.9)
Prostate	1 (5.9)
Thyroid	1 (5.9)
Age of second diagnosed tumor	Mean (minimum-maximum)
	59 (49-69)
Second primary diagnosed tumor site
Colorectal	2 (11.8)
Breast	1 (5.9)
Thyroid	1 (5.9)
Status
Alive, in follow-up	26 (96.3)
Deceased	1 (3.7)

¹Total number of cancers affected patients is 17.