Histone deacetylases 10 as a prognostic biomarker correlates with tumor microenvironment and therapy response in colorectal cancer

doi:10.3748/wjg.v31.i26.108662

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Jul 14, 2025 (publication date) through Jul 28, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2025; 31(26): 108662
Published online Jul 14, 2025. doi: 10.3748/wjg.v31.i26.108662

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Figure 4 Differential analysis and functional enrichment analysis. A: Volcano plot from the top five upregulated and downregulated differentially expressed genes (DEGs) between high and low-histone deacetylases 10 group; B: Heat map showed the top five genes in both upregulated and downregulated DEGs; C: Different expression levels of DEGs between normal colon and colorectal cancer; D: Gene set variation analysis showed the activation status of biological pathways in two groups. HDAC10: Histone deacetylases 10.

Citation: Nie HH, Yang XY, Zhou JK, Gao GL, Ding L, Hong YT, Yu YL, Qiu PS, Zeng ZY, Lai J, Zheng T, Wang HZ, Zhao Q, Wang F. Histone deacetylases 10 as a prognostic biomarker correlates with tumor microenvironment and therapy response in colorectal cancer. World J Gastroenterol 2025; 31(26): 108662
URL: https://www.wjgnet.com/1007-9327/full/v31/i26/108662.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i26.108662