Risk factors and diagnostic biomarkers for asymptomatic immune checkpoint inhibitor-related myocarditis in patients with esophageal cancer after immunotherapy

Table 3 Cardiac biomarkers, mean ± SD

Parameters	Non-occurrence group (n = 134)	Occurrence group (n = 68)	t value	P value
Cardiac troponin I (ng/mL)	0.07 ± 0.03	0.07 ± 0.04	0.112	0.911
CK-MB (ng/mL)	3.05 ± 0.95	5.02 ± 1.49	25.032	< 0.001
CK (U/L	187.29 ± 58.25	212.25 ± 62.55	2.808	0.005
LDH (U/L)	210.35 ± 42.38	219.15 ± 41.94	1.400	0.163
Myoglobin (ng/mL)	60.58 ± 12.59	62.68 ± 13.96	1.082	0.280
NT-proBNP (pg/mL)	185.48 ± 36.89	194.13 ± 42.16	1.500	0.135

CK: Creatine kinase; LDH: Lactate dehydrogenase; NT-proBNP: N-terminal pro-B-type natriuretic peptide.