Multiparametric ultrasound for non-invasive assessment of liver steatosis, fibrosis, and inflammation in metabolic dysfunction-associated steatotic liver disease

Table 3 Univariate and multivariate analysis evaluating variables associated with metabolic dysfunction-associated steatohepatitis

Variable	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Sex (male)	0.74 (0.34-1.62)	0.45
Age	0.98 (0.95-1.02)	0.48
Att.PLUS	0.03 (0.01-1.06)	0.06
SSp.PLUS	0.98 (0.97-0.99)	< 0.01	0.98 (0.97-0.99)	< 0.01
CAP	1.02 (1.01-1.03)	< 0.01
Vi.PLUS	3.59 (1.47-8.78)	< 0.01	3.12 (1.20-8.16)	0.02
BMI (kg/m2)	1.05 (0.99-1.11)	0.11
Triglycerides	1.00 (0.99-1.01)	0.11
Total cholesterol	1.00 (0.99-1.01)	0.94
Diabetes	2.42 (0.95-6.17)	0.06
Hypertension	1.74 (0.79-3.82)	0.16
ALT	1.02 (1.01-1.03)	0.01	1.03 (1.01-1.06)	0.05
AST	1.03 (1.01-1.06)	0.02

OR: Odds ratio; CI: Confidence interval; Att.PLUS: Attenuation plane-wave ultrasound; SSp.PLUS: Sound speed plane-wave ultrasound; CAP: Controlled attenuation parameter; Vi.PLUS: Viscosity plane-wave ultrasound; BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.