Multi-parameter magnetic resonance imaging of zebularine in liver fibrosis treatment and calcineurin/NFAT3 mechanism

Figure 12  Masson’s staining showing the effect of carbon tetrachloride and zebularine treatment on collagen fibers in mouse liver tissue. A: Representative images of liver sections stained with Masson’s trichrome; B: Collagen fiber percentage at 2, 4, and 6 weeks; C: METAVIR fibrosis grading at 2, 4, and 6 weeks (n = 12 mice/group). Original magnification: × 200. ^aP < 0.05. ^bP < 0.01. ^dP < 0.0001. ¹P vs control. ²P vs carbon tetrachloride. CCl₄: Carbon tetrachloride.