Multi-parameter magnetic resonance imaging of zebularine in liver fibrosis treatment and calcineurin/NFAT3 mechanism

Table 3 Sequence-specific parameters

Parameter/sequence	T1WI	T2WI	EPI-DWI	T1 MAP	T2 MAP
TR	585	3243	2000	15	3000
TE	11.32	87.38	80	3.87	17.4, 34.8, 52.2, 69.6, 87.0, 104.4
Flip angle (°)	150°	140°	90°	5°, 25°	180°
Voxel size (mm³) (X × Y × Z)	0.16 × 0.16 × 1	0.30 × 0.30 × 1	0.59 × 0.59 × 2	0.13 × 0.13 × 1	0.50 × 0.50 × 2
FOV (mm²)	40 × 40	40 × 40	50 × 80	75 × 83	90 × 100
Slices	20	20	15	20	15
Acquisition time	4:47	5:24	3:22	3:8	5:39

T1WI: T1-weighted imaging; T2WI: T2-weighted imaging; EPI: Echo planar imaging; DWI: Diffusion-weighted imaging; TR: Repetition time; TE: Echo time; FOV: Field of view; T1 MAP: T1 mapping; T2 MAP: T2 mapping.