Case Report
Copyright ©The Author(s) 2025.
World J Gastroenterol. May 14, 2025; 31(18): 103778
Published online May 14, 2025. doi: 10.3748/wjg.v31.i18.103778
Table 1 Clinical characteristics of all reported cases of idiopathic myointimal hyperplasia of the mesenteric veins to date
Case
Ref.
Age (year)/sex
Symptoms
Affected site
Clinical impression
Indication for surgery
Time to surgery
Follow-up
1Current case50/FAbdominal pain, abdominal distensionTerminal ileumCDBowel obstruction6 years (this operation)/1 year (the first operation)1 month
2Li et al[7]64/MAbdominal pain, abdominal distension, weight lossTerminal ileumIBDBowel obstruction6 months1 year
3Yamada et al[24]81/FAbdominal pain, nausea and vomitingTerminal ileumAdhesive intestinal obstructionBowel obstruction1 year32 months
4Guadagno et al[47]59/FAbdominal pain, diarrhea, weight lossIleumCDBowel obstruction6 months3 months
5Laskaratos et al[25]62/FAbdominal pain, diarrheaTerminal ileumIBDPerforation--
6Lanitis et al[37]81/MAbdominal pain, abdominal distension, constipation, weight loss, anorexia, bilateral lower limb edemaTerminal ileum-Appendiceal mucocoele and pseudomyxoma peritonei6 months-
7Bryant[30]42/FChest pain, seizuresJejunum----
8Louie et al[27]57/FAbdominal pain, nauseaJejunum/ileum-CT scan showed bowel ischemia-24 months
9Martin et al[43]63/MDiarrhea, hematochezia, weight loss, feverRectum - DCICPersisting symptoms3.75 months-
10-13Lincango et al[42]Mean 55 (range 45-61)/4 MAbdominal pain (n = 3), diarrhea (n = 1), fever (n = 1), tenesmus (n = 2), rectal pain (n = 1), constipation and diarrhea alternated (n = 2), back pain (n = 1), abdominal distention (n = 1), weight loss (n = 1), nausea (n = 1)Rectum - DC (n = 1), SC (n = 1), SC - DC (n = 1), RS (n = 1)UC (n = 2), IC (n = 1), UC/IC (n = 1)Medically refractory (n = 3), bowel obstruction (n = 1)> 10 days (n = 1)Mean 69 months (range 12-144 months)
14Al Ansari et al[18]63/MAbdominal pain, diarrheaSC - DCEntamoeba histolytica colitisPersisting symptoms41 days5 years
15-26Kim et al[19]Mean 66 (range 58-77)/11 M and 1FAbdominal pain (n = 10), diarrhea (n = 9), constipation (n = 3), mucoid stools (n = 3), perianal pain (n = 1), weight loss (n = 1), fever (n = 2), tenesmus (n = 1), abdominal distension (n = 1)RS (n = 9), rectum - DC (n = 2), TC - terminal ileum (n = 1)IC (n = 4); UC (n = 1), nonspecific colitis (n = 1), CMV colitis (n = 1), idiopathic phlebosclero colitis (n = 1), IMHMN (n = 3)-Mean 3 months (range 1-8 months)Mean 29 months (range 2-125 months)
27Chudy-Onwugaje et al[48]54/MAbdominal pain, diarrhea, weight lossTCCMV colitisPersisting symptoms4 months-
28Zhou et al[44]67/MAbdominal pain, diarrhea, hematochezia, weight lossRectum - DCUCPersisting symptoms6.25 months-
29Han et al[31]74/MAbdominal pain, diarrhea, hematochezia, weight lossRectum - TCIMHMVPersisting symptoms, IMHMV was suspected1 year5.5 months
30Kelly et al[38]53/MAbdominal pain, hematochezia, weight loss, tenesmusRectum - DCUC/IMHMVPersisting symptoms3 months3 months
31Noujaim et al[49]66/MAbdominal pain, diarrhea, hematochezia, weight loss, fever, night sweatsRectum - DCIBD/IMHMV/C. difficile infectionAcute abdomen> 2 monthsDied on postoperative day 4
32Yun et al[20]64/MAbdominal pain, diarrhea, hematocheziaRectum - TCNon-thrombotic veno-occlusive disease, such as IMHMVIMHMV was suspected2 years6 months
33Almumtin et al[46]55/MAbdominal pain, hematochezia, weight loss, constipation, feverRectum - TCIBDPerforation1 year-
34Shah et al[12]24/FAbdominal pain, hematocheziaRectum - DCICAbdominal pain/perforation> 1 month-
35Kawasaki et al[17]71/MAbdominal pain, constipationRSIMHMVIMHMV was suspected4 months8 months
36Wong et al[21]72/MAbdominal pain, diarrhea, hematocheziaRectum - DCIC/IMHMVAcutely worsening abdominal pain with peritoneal signsSeveral days-
37Dillione et al[50]47/MAbdominal pain, hematocheziaRSIschemic proctitisPersisting symptomsSeveral weeks-
38Wangensteen et al[28]62/FAbdominal pain, diarrhea, hematocheziaRectum - DCUC (initial)/IMHMVPersisting symptoms, IMHMV was suspected> 3 months1.5 years
39-48Yantiss et al[35]Mean 68 (range 25-83)/9 M and 1FAbdominal pain (n = 6), diarrhea (n = 10), hematochezia (n = 9), weight loss (n = 2), Palpable mass (n = 1)Rectum - DC (n = 7), SC (n = 1), SC - DC (n = 1)IC/IBD (n = 1), IBD (n = 7), IC (n = 2)Perforation (n = 5), obstruction and refractory colitic symptoms--
49AbiMansour et al[40]59/MAbdominal pain, diarrhea, urgencySCDiverticulitisPersisting symptoms1 year-
50Patel et al[51]65/MAbdominal pain, rectal urgency, tenesmusRectum - DCCD/IMHMVPerforation> 1.5 months-
51Morimura et al[11]44/MAbdominal pain, constipation, feverRectum - TCIBD/Eosinophilic enteritisBowel ischemia and necrosis with peritonitis> 1 month1 year
52Xie et al[52]21/FAbdominal pain, diarrhea, hematochezia, fever, tenesmusRSAcute IBDMassive hematochezia, shock> 20 days2 years
53Cauchois et al[53]48/MAbdominal pain, diarrhea, hematochezia, fever, weight lossRSUCPersistent symptoms5 months-
54Costa et al[33]47/MAbdominal pain, diarrhea, hematochezia, fever, tenesmus, proctalgia, fecal incontinenceRSIBD/ICPersistent symptoms9 months-
55-62Anderson et al[34]Median 62.5 (range 22-75)/6 M and 2FAbdominal pain (n = 7), diarrhea (n = 5), hematochezia (n = 4)SC (n = 6)IBD (n = 3)---
63Mohtashami et al[45]61/MAbdominal pain, diarrhea, hematochezia, abdominal distensionRectum - DCCDPerforation3 weeks-
64Gonai et al[54]68/MAbdominal distension, constipation, mucoid stoolsSC - DCChronic venous ischemic diseasePersistent symptoms--
65Sahara et al[1]76/MAbdominal pain, diarrheaRSUC/ICSevere pain13 months3 months
66García-Castellanos et al[32]32/FAbdominal pain, diarrhea, hematocheziaRectum - DCPrimary pneumatosis intestinalis, ICPersistent rectal bleeding, severe pain3 months24 months
67Feo et al[55]75/FAbdominal pain, diarrhea, hematochezia, weight loss, tenesmusRSICPersistent symptoms6 months-
68Bhatt et al[29]82/MAbdominal distension, diarrhea, erratic bowel movements, urgency, mucoid stools, weight lossRectum - DCICPersistent symptoms3 months> 1 year
69Bhatt et al[29]59/MDiarrhea, tenesmusRSDiverticulitis (initial)/IMHMVPersistent symptoms/ MRI suggested IMHMV-> 1 year
70Abbott et al[56]58/MAbdominal pain, diarrhea, hematocheziaRectum - DCEntameba histolytica infection/IBDPersistent symptomsSeveral weeks-
71-74Genta and Haggitt[3]Mean 40 (range 25-67)/4 MAbdominal pain (n = 4), hematochezia (n = 4), constipation and diarrhea alternated (n = 3)SC (n = 1), Rectum - DC (n = 1), RS (n = 2)UC (n = 2), CD (n = 1), Stricture (n = 1)Bowel obstruction (n = 1), toxic megacolon (n = 1), abdominal pain and hematochezia (n = 2)Mean 3 months (range 1-6 months)Mean 3.5 years (range 1-7 years)
75Kao et al[9]38/MAbdominal pain, rectalgia, constipation, hematochezia, mucoid stools, weight lossRSIdiopathic chronic IBDPerforation5 months18 months
76Yang et al[22]44/MAbdominal pain, diarrhea, hematocheziaRSUC/ICPersistent symptoms2 months-
77Savoie et al[57]22/MAbdominal pain, diarrhea, hematochezia, tenesmusRSUCPersistent symptoms> 2 weeks10 months
78Abu-Alfa et al[4]58/MAbdominal pain, diarrhea, hematocheziaSCIBD/ICPersistent bleeding, severe pain1 year-
79Chiang et al[39]60/MAbdominal pain, diarrhea, hematochezia, weight lossRSUCPersistent symptoms2 months4 months
80Coombs et al[23]33/MAbdominal pain, constipation, hematocheziaRSICPersistent rectal bleeding and abdominal pain4 weeks-
81Uwah et al[36]37/MAbdominal pain, constipation and diarrhea alternated, hematocheziaRectum - DCIBD/ICPersistent symptoms/stricture> 2 months-
82Uwah et al[36]49/MAbdominal pain, diarrhea, hematocheziaRectum - DCColitis of unknown etiologyPersistent symptomsSeveral months-
83López et al[58]37/FAbdominal pain, diarrheaRectum - terminal ileumCDAcute abdomen7 monthsDied
84Song et al[26]59/MAbdominal pain, abdominal distension, constipation and diarrhea alternated, IncontinenceRectum - terminal ileumCDPersistent symptoms--
85Louie et al[27]45/MLower gastrointestinal bleedingRSUC---