Ozone controls the metabolism of tryptophan protecting against sepsis-induced intestinal damage by activating aryl hydrocarbon receptor

Figure 3 Ozone-rich water alleviation of sepsis-induced intestinal injury is dependent on the intestinal flora. A and B: Hematoxylin-eosin staining; C and D: Zonula occludens-1 and occludin levels, shown by immunofluorescence staining; E and F: Interleukin-6 and tumor necrosis factor-α levels in the colon, shown by immunohistochemistry; G and H: Immunofluorescence staining of cluster of differentiation (CD) 86 and CD206. ^bP < 0.01. ^cP < 0.001. CLP: Cecal ligation and puncture; IL-6: Interleukin-6; CD: Cluster of differentiation; ABX: Antibiotics; TNF-α: Tumor necrosis factor-α; ZO-1: Zonula occludens-1.