Staging liver fibrosis with various diffusion-weighted magnetic resonance imaging models

Figure 3 The detailed comparisons of Mono-apparent diffusion coefficient, intravoxel incoherent motion model-derived true diffusion coefficient, fractional order calculus model-derived diffusion coefficient and continuous-time random-walk model-derived anomalous diffusion coefficient in different stages of liver fibrosis. A-D: Box-and-whisker plots showing the distributions of Mono-apparent diffusion coefficient (A), intravoxel incoherent motion model-derived true diffusion coefficient (B), fractional order calculus model-derived diffusion coefficient (C), and continuous-time random-walk model-derived anomalous diffusion coefficient (D) in various liver fibrosis stages (^aP < 0.05). ADC: Apparent diffusion coefficient; IVIM-D: Intravoxel incoherent motion model-derived true diffusion coefficient; FROC-D: Fractional order calculus model-derived diffusion coefficient; CTRW-D: Continuous-time random-walk model-derived anomalous diffusion coefficient.