Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery

doi:10.3748/wjg.v30.i12.1714

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Mar 28, 2024 (publication date) through May 11, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2024; 30(12): 1714-1726
Published online Mar 28, 2024. doi: 10.3748/wjg.v30.i12.1714

Table 5 Univariate and multivariate analysis of disease-free survival

Risk factors	Univariate analysis		Multivariate analysis
Risk factors	HR (95%CI)	P value	HR (95%CI)	P value
Age (yr)	1.031 (1.025-1.038)	< 0.01^a	1.027 (1.020-1.033)	< 0.01^a
Sex (female/male)	0.861 (0.730-1.015)	0.058
BMI (kg/m²)	0.975 (0.953-0.997)	0.029^a	1.003 (0.981-1.026)	0.784
T2DM (yes/no)	1.127 (0.911-1.396)	0.271
Tumor site (colon/ rectum)	1.126 (0.975-1.300)	0.107
Tumor stage (IV/III/II/I)	2.120 (1.926-2.334)	< 0.01^a	2.093 (1.900-2.307)	< 0.01^a
Smoking (yes/no)	1.093 (0.944-1.267)	0.234
Drinking (yes/no)	1.104 (0.946-1.288)	0.208
Hypertension (yes/no)	1.036 (0.879-1.220)	0.676
CHD (yes/no)	1.281 (0.917-1.791)	0.147
Tumor size (≥ 5 cm/< 5 cm)	1.363 (1.180-1.574)	< 0.01^a	1.115 (0.962-1.294)	0.149
RDW (lower/higher)	0.713 (0.616-0.824)	< 0.01^a	0.920 (0.783-1.080)	0.308
Hematocrit (lower/higher)	1.509 (1.304-1.747)	< 0.01^a	1.194 (1.013-1.408)	0.035^a
Overall complications (yes/no)	1.705 (1.463-1.987)	< 0.01^a	1.510 (1.293-1.763)	< 0.01^a

^aP value < 0.05.

RDW: Red blood cell distribution width; HR: Hazard ratio; CI: Confidence interval; BMI: Body mass index; T2DM: Type 2 diabetes mellitus; CHD: Coronary heart disease.

Citation: Peng D, Li ZW, Liu F, Liu XR, Wang CY. Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery. World J Gastroenterol 2024; 30(12): 1714-1726
URL: https://www.wjgnet.com/1007-9327/full/v30/i12/1714.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i12.1714