Gaseous metabolites as therapeutic targets in ulcerative colitis

doi:10.3748/wjg.v29.i4.682

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Jan 28, 2023 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2023; 29(4): 682-691
Published online Jan 28, 2023. doi: 10.3748/wjg.v29.i4.682

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Figure 1 Proposed mechanisms of microbial metabolites, hydrogen sulfide and nitric oxide, in the pathogenesis of ulcerative colitis via a dysfunctional colonic epithelium and breakdown in mucosal barrier function. Figure summarised from references[8,55-57]. CHO: Carbohydrate; H₂S: Hydrogen sulfide; SRB: Sulfate-reducing bacteria; H₂S: Hydrogen sulfide; IL: Interleukin.

Citation: Yao CK, Sarbagili-Shabat C. Gaseous metabolites as therapeutic targets in ulcerative colitis. World J Gastroenterol 2023; 29(4): 682-691
URL: https://www.wjgnet.com/1007-9327/full/v29/i4/682.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i4.682