MiR-204-3p overexpression inhibits gastric carcinoma cell proliferation by inhibiting the MAPK pathway and RIP1/MLK1 necroptosis pathway to promote apoptosis

Figure 7 Effect of miR-204-3p on the MAPK signaling pathway in AGS and HGC-27 cells. A and B: Effects of miR-204-3p on mRNA levels of KRAS, ERK1 and ERK2 in AGS and HGC-27 cells; C and D: Effects of miR-204-3p on protein levels of KRAS, ERK1/2 and p-ERK1/2 in AGS cells; E and F: Effects of miR-204-3p on protein levels of KRAS, ERK1/2 and p-ERK1/2 in HGC-27 cells. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. NC: Empty lentiviral vector; KD: miR-204-3p knockdown lentiviral vector; OE: miR-204-3p overexpression lentiviral vector.