Older adults with acute severe ulcerative colitis have similar steroid non-response and colectomy rates as younger adults

Table 2 Summary of primary and secondary outcomes of older vs younger adults with acute severe ulcerative colitis, n (%)

	≥ 60 yr, n = 45	< 60 yr, n = 181	Crude RD (95%CI)	Crude RR (95%CI)	Adjusted RR1 (95%CI)	OR (95%CI)
Primary outcome: Steroid non-response	19 (42.2%)	85 (47%)	-0.47 (-0.21 to 0.11)	0.89 (0.61-1.30)	0.99 (0.34-2.90)	0.82 (0.43-1.58)
Response to medical rescue therapy	13 (76.5%)	66 (85.7%)	-0.09 (-0.31 to 0.12)	0.89 (0.67-1.17)	-	0.54 (0.16-1.85)
Colectomy same admission	6 (13.3%)	19 (10.5%)	0.028 (-0.08 to 0.13)	1.27 (0.53-2.99)	1.43 (0.34-6.06)	1.31 (0.50-3.41)
Colectomy at 3 mo	9 (20.9%)	30 (17.6%)	-0.03 (-0.10 to 0.16)	1.18 (0.61-2.3)	1.31 (0.32-5.30)	1.23 (0.54-2.80)
Colectomy at 12 mo	9 (24.3%)	42 (28.8%)	-0.04 (-0.20 to 0.11)	0.85 (0.45-1.57)	1.2 (0.29-4.97)	0.79 (0.35-1.80)

¹Adjusted relative risk for sex, disease duration, smoking status, disease extent, current biologic use.

RD: Risk difference; RR: Relative risk; aRR: Adjusted relative risk; OR: Odds ratio.