Endoscopic mucosal resection-precutting vs conventional endoscopic mucosal resection for sessile colorectal polyps sized 10-20 mm

Table 2 Procedure-related outcomes in this study

Parameter	EMR-P group, %	CEMR group, %	P value
ITT analysis	n = 110	n = 110
En bloc resection	103 (93.6) [87.5-96.9]	95 (86.4) [78.7-91.6]	0.072
R0 resection	89 (80.9) [72.6-87.2]	86 (78.2) [69.6-84.9]	0.616
R1 resection	9 (8.2) [4.4-14.8]	9 (8.2) [4.4-14.8]	> 0.999
RX resection	6 (5.5) [2.5-11.4]	6 (5.5) [2.5-11.4]	> 0.999
PP analysis	n = 106	n = 107
En bloc resection	100 (94.3) [88.2-97.4]	92 (86.0) [78.2-91.3]	0.041
R0 resection	86 (81.1) [72.6-87.4]	83 (77.6) [68.8-84.4]	0.521
R1 resection	9 (8.4) [4.5-15.4]	9 (8.5) [4.5-15.2]	0.983
RX resection	6 (5.7) [2.6-11.8]	6 (5.6) [2.6-11.7]	0.987
Histological type, n (%)	n = 110	n = 110	0.354
Adenoma	82 (74.5)	85 (77.3)
Tubular adenoma with low-grade dysplasia	62 (56.4)	63 (57.3)
Tubular adenoma with high-grade dysplasia	6 (5.5)	7 (6.4)
Villous adenoma with low-grade dysplasia	2 (1.8)	1 (0.9)
Villous adenoma with high-grade dysplasia	0 (0.0)	0 (0.0)
Tubular villous adenoma with low-grade dysplasia	10 (9.1)	12 (10.9)
Tubular villous adenoma with high-grade dysplasia	2 (1.8)	2 (1.8)
Hyperplastic	11 (10.0)	14 (12.7)
Serrated lesions	9 (8.2)	7 (6.4)
Cancer	4 (3.6)	4 (3.6)
Intramucosal adenocarcinoma	3 (2.7)	4 (3.6)
Submucosal invasive adenocarcinoma	1 (0.9)	0 (0.0)
Other	4 (3.6)	0 (0.0)
Procedure time (min)	6.4 (4.5, 10.3)	3.0 (1.9, 6.2)	< 0.001

EMR-P: Endoscopic mucosal resection with circumferential precutting; CEMR: Conventional endoscopic mucosal resection; ITT: Intention-to-treat analysis; PP: Per-protocol analysis; En bloc resection is defined as a once-piece resection; R0 resection is defined as en bloc resection with a histologically negative margin; R1 resection is defined as a positive resection margin; RX resection is defined as an unknown resection status.