Retrospective Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Oct 7, 2022; 28(37): 5469-5482
Published online Oct 7, 2022. doi: 10.3748/wjg.v28.i37.5469
Table 3 Univariable and multivariable logistic regression analyses of the risk factors for high risk of malignancy in patients with pancreatic cystic neoplasms
VariableOR comparisonsUnivariable analysis
Multivariable analysis
OR (95%CI)
P value
OR (95%CI)
P value
SexFemale vs Male2.383 (1.054-5.386)0.037a0.716 (0.232-2.213)0.562
Age in yr≥ 60 vs < 602.180 (0.967-4.915)0.060
BMI0.986 (0.874-1.111)0.816
Weight lossYes vs No2.437 (0.861-6.897)0.093
AlcoholYes vs No2.252 (0.741-6.845)0.153
SymptomaticYes vs No1.774 (0.737-4.271)0.201
Tumor involve the head of pancreasYes vs No1.148 (0.487-2.705)0.753
Bile duct dilationYes vs No1.788 (0.460-6.952)0.402
Tumor diameter in mm≥ 40 vs < 404.094 (1.649-10.165)0.002a3.514 (1.138-10.849)0.029a
Intratumoral septumYes vs No0.539 (0.240-1.211)0.135
Cyst wall enhancementYes vs No1.127 (0.494-2.569)0.777
Cyst wall thickeningYes vs No1.670 (0.329-8.488)0.536
Enhanced mural nodulesYes vs No6.490 (2.746-15.342)< 0.001a4.314 (1.618-11.503)0.003a
Intracapsular calcificationYes vs No0.208 (0.027-1.606)0.132
Main pancreatic duct dilatationYes vs No3.574 (1.558-8.201)0.003a3.267 (1.230-8.678)0.018a
NLR≥ 2.288 vs < 2.2883.077 (1.350-7.015)0.008a2.702 (1.008-7.244)0.048a
TB in μmol/L≥ 34.2 vs < 34.26.240 (1.192-32.657)0.030a0.870 (0.050-15.020)0.924
ALP in IU/L≥ 200 vs < 2009.420 (1.499-59.213)0.017a0.632 (0.064-6.285)0.695
GGT in IU/L≥ 150 vs < 1502.925 (0.931-9.189)0.066
CEA in ng/mL≥ 5 vs < 56.955 (2.060-23.477)0.002a3.798 (0.825-17.482)0.087
CA199 in U/mL≥ 34 vs < 344.547 (1.750-11.816)0.002a3.267 (1.274-13.007)0.018a