Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between laminin-γ2 and integrin-β1

Figure 4 Quantification of the protein levels of epithelial mesenchymal transformation-related markers in colorectal cancer rats by using western blotting. The bars represent the mean ± SD (n = 3). A: The western blotting images of phosphorylate-focal adhesion kinase (p-FAK), FAK, snail, fibronectin, E-cadherin, N-cadherin and special AT-rich sequence binding protein 1 (SATB1) in animal samples; B: Quantification of the protein levels of FAK, p-FAK/FAK, snail, fibronectin, E-cadherin, N-cadherin and SATB1 in animal samples. Compared with the non-alcohol group: ^bP < 0.01, ^aP < 0.05. SATB1: Special AT-rich sequence binding protein 1; FAK: Focal adhesion kinase; p-FAK: Phosphorylate focal adhesion kinase; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.