Eliminating viral hepatitis in children after liver transplants: How to reach the goal by 2030

Table 3 Recommended direct-acting antiviral regimens for children who are naïve to or experienced with direct-acting antiviral therapy[101,102]

Age	Genotype	No cirrhosis/ cirrhosis	Recommended regimens of DAAs	Duration (wk)
12-17 yr	Pan-genotypes	No cirrhosis	Sofosbuvir 400 mg/ velpatasvir 100 mg	12
		Compensated cirrhosis (Child-Pugh A)	Glecaprevir 300 mg/pibrentasvir 120 mg	8-12
12-17 yr or BW ≥ 35 kg	1, 4, 5, 6	No cirrhosis	Sofosbuvir 400 mg/ledipasvir 90 mg	12
		Compensated cirrhosis (Child-Pugh A)	Sofosbuvir 200 mg/velpatasvir 50 mg (BW ≥ 17 kg)
3-11 yr	Pan-genotypes	No cirrhosis	Sofosbuvir 150 mg/velpatasvir 37.5 mg (BW < 17 kg)	12
		Compensated cirrhosis (Child-Pugh A)	Glecaprevir 250 mg/pibrentasvir 100 mg (BW 30-44 kg); Glecaprevir 200 mg/pibrentasvir 80 mg (BW 20-29 kg); Glecaprevir 150 mg/pibrentasvir 60 mg (BW 12-19 kg)	12; 8-16; 8-16; 8-16;

BW: Body weight.