Activation of natural killer T cells contributes to Th1 bias in the murine liver after 14 d of ethinylestradiol exposure

Figure 4 Absence of invariant natural killer T cells alters the expression of toll-like receptors. A-E: Hepatic mRNA levels of Tlr2 (A), Tlr4 (B), Tlr6 (C), Tlr7 (D) and Tlr9 (E) were determined and compared; F: Changes in the protein level of TLR9 were determined by immunohistochemistry. All values are the means ± SE (n = 4-6). ^bP < 0.01, ^cP < 0.001 vs control; ^eP < 0.01, ^fP < 0.001 vs C57BL/6J group.