Activation of natural killer T cells contributes to Th1 bias in the murine liver after 14 d of ethinylestradiol exposure

Figure 2 Invariant natural killer T cells exacerbate ethinylestradiol-induced cholestatic liver damage. A-D: The serum levels of ALP (A), TBA (B), ALT (C) and AST (D); E: Liver sections stained with hematoxylin and eosin (10×); F: Proliferation of pseudocholangiolar duct (yellow arrows); G and H: Inflammatory cell infiltration (G, red arrows) and hepatocyte necrosis (H, black arrows) were compared as pathology scores. All values are the means ± SE (n = 4-6). ^bP < 0.01, ^cP < 0.001 vs control; ^eP < 0.01, ^fP < 0.001 vs C57BL/6J group.