Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome: A multicenter retrospective study

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Jun 7, 2022; 28(21): 2334-2349
Published online Jun 7, 2022. doi: 10.3748/wjg.v28.i21.2334

Table 1 Strategy for computing the single-nucleotide polymorphism score

	Major allele homozygous genotype	Heterozygous variant genotype	Minor allele homozygous genotype
HTR3A c.-42C>T (rs1062613)	CC	CT	TT
HTR3B c.386A>C (rs1176744)	AA	AC	CC
HTR3C c.489C>A (rs6766410)	CC	CA	AA
HTR3E c.*76G>A (rs56109847)	GG	GA	AA

Citation: Berens S, Dong Y, Fritz N, Walstab J, D'Amato M, Zheng T, Wahl V, Boekstegers F, Bermejo JL, Martinez C, Schmitteckert S, Clevers E, Engel F, Gauss A, Herzog W, Spiller R, Goebel-Stengel M, Mönnikes H, Andresen V, Thomas F, Keller J, Pehl C, Stein-Thöringer C, Clarke G, Dinan TG, Quigley EM, Sayuk G, Simrén M, Tesarz J, Rappold G, van Oudenhove L, Schaefert R, Niesler B. Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome: A multicenter retrospective study. World J Gastroenterol 2022; 28(21): 2334-2349
URL: https://www.wjgnet.com/1007-9327/full/v28/i21/2334.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i21.2334

Berens S, Dong Y, Fritz N, Walstab J, D'Amato M, Zheng T, Wahl V, Boekstegers F, Bermejo JL, Martinez C, Schmitteckert S, Clevers E, Engel F, Gauss A, Herzog W, Spiller R, Goebel-Stengel M, Mönnikes H, Andresen V, Thomas F, Keller J, Pehl C, Stein-Thöringer C, Clarke G, Dinan TG, Quigley EM, Sayuk G, Simrén M, Tesarz J, Rappold G, van Oudenhove L, Schaefert R, Niesler B. Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome: A multicenter retrospective study. World J Gastroenterol 2022; 28(21): 2334-2349 [PMID: 35800179 DOI: 10.3748/wjg.v28.i21.2334]

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