Minireviews
Copyright ©The Author(s) 2022.
World J Gastroenterol. Apr 7, 2022; 28(13): 1304-1314
Published online Apr 7, 2022. doi: 10.3748/wjg.v28.i13.1304
Table 1 TNM staging for appendiceal neuroendocrine tumor according to European Neuroendocrine Tumor Society and American Joint Committee on Cancer classification

ENETS
AJCC
T0No evidence of primary tumorNo evidence of primary tumor
T1Tumor ≤ 1 cm with infiltration of submucosa and muscularis propia
T1aTumor ≤ 1 cm
T1bTumor 1-2 cm
T2Tumor ≤ 2 cm with infiltration of the submucosa, muscularis propia and/or minimal (≤ 3 mm) infiltration of the subserosa and/or mesoappendixTumor 2-4 cm or with extension into the cecum
T3Tumor > 2 cm and/or extensive (> 3 mm) infiltration of the subserosa and/or mesoappendixTumor > 4 cm or with extension into the ileum
T4Tumor with infiltration of the peritoneum and/or other neighboring organsTumor with perforation of the peritoneum or invasion of other adjacent structures
N0No regional lymph node metastasisNo regional lymph node metastasis
N1Locorregional lymph node metastasisLocorregional lymph node metastasis
M0No distant metastasisNo distant metastasis
M1Distant metastasisDistant metastasis