Digestive system involvement and clinical outcomes among COVID-19 patients: A retrospective cohort study from Qatar

doi:10.3748/wjg.v27.i46.7995

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Dec 14, 2021; 27(46): 7995-8009
Published online Dec 14, 2021. doi: 10.3748/wjg.v27.i46.7995

Table 5 Association of gastrointestinal symptoms with individual drugs, n (%)

	Azithromycin (n = 538)	HCQ (n = 540)	*Antibiotics (n =* 493)**	*Steroids (n =* 248)**	*RBV (n =* 91)**	*Tocilizumab (n =* 236)**	*L/r (n =* 340)**	*Oseltamivir (n =* 510)**
Diarrhea	78 (14.50)	79 (14.63)	70 (14.20)	37 (14.92)	24 (26.37)P < 0.001^a	35 (14.83)	44 (12.94)	75 (14.71)
Nausea	160 (29.74)	165 (30.60)	147 (29.82)	74 (29.84)	26 (8.57)	66 (27.97)	111 (32.65)P = 0.049^a	153 (30.00)
Vomiting	148 (27.51)	154 (28.52)P = 0.009^a	135 (27.38)	68 (27.42)	22 (24.18)	64 (27.12)	107 (31.47)P = 0.004^a	140 (27.45)
Epigastric pain	57 (10.59)	60 (11.11)	54 (10.95)	29 (11.69)	13 (14.29)	24 (10.17)	43 (12.65)P = 0.048^a	55 (10.78)
Anorexia	55 (10.22)	58 (10.74)	50 (10.14)	30 (12.10)	16 (17.58)P = 0.022^a	28 (11.86)	41 (12.06)	56 (10.98)
Any GI symptoms	208 (38.66)	209 (38.70)	191 (38.74)	95 (38.31)	41 (45.05)	92 (38.98)	138 (40.59)	194 (38.04)

^aStatistically significant P value.

HCQ: Hydroxychloroquine; RBV: Ribavirin; L/r: Lopinavir/ritonavir; GI: Gastrointestinal

Citation: Khan MU, Mushtaq K, Alsoub DH, Iqbal P, Ata F, Chaudhry HS, Iqbal F, Balaraju G, Maslamani MAA, Varughese B, Singh R, Ejji KA, Kaabi SA, Kamel YM, Butt AA. Digestive system involvement and clinical outcomes among COVID-19 patients: A retrospective cohort study from Qatar. World J Gastroenterol 2021; 27(46): 7995-8009
URL: https://www.wjgnet.com/1007-9327/full/v27/i46/7995.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i46.7995