Clinicopathological characteristics and longterm survival of patients with synchronous multiple primary gastrointestinal stromal tumors: A propensity score matching analysis

Table 1 Preoperative clinical characteristics of solitary gastrointestinal stromal tumors and multiple gastrointestinal stromal tumors in the entire cohort and after propensity score matching

Parameters	Entire cohort, before matching		P value	Propensity score matched cohort		P value
	SGIST, n (%)	MGIST, n (%)		SGIST, n (%)	MGIST, n (%)
All cases	942	41		164	41
Age (yr)			0.450			0.889
≤ 60	516 (54.78)	20 (48.78)		82 (50.00)	20 (48.78)
> 60	426 (45.22)	21 (51.22)		82 (50.00)	21 (51.22)
Gender			0.060			0.596
Male	479 (50.85)	27 (65.85)		115 (70.12)	27 (65.85)
Female	463 (49.15)	14 (34.15)		49 (29.88)	14 (34.15)
BMI (kg/m2)			0.010			0.193
BMI < 18.5	41 (4.35)	6 (14.63)		11 (6.71)	6 (14.63)
18.5 ≤ BMI < 25	501 (53.18)	19 (46.34)		94 (57.32)	19 (46.34)
BMI ≥ 25	400 (42.46)	16 (39.02)		59 (35.98)	16 (39.02)
Tobacco use			0.899			0.093
No	704 (74.73)	31 (75.61)		101 (61.59)	31 (75.61)
Yes	238 (25.27)	10 (24.39)		63 (38.41)	10 (24.39)
Alcohol use			0.514			0.768
No	687 (72.93)	28 (60.98)		108 (65.85)	28 (60.98)
Yes	255 (27.07)	13 (31.71)		56 (34.15)	13 (31.71)
ASA score			0.443			0.868
I/II	779 (82.70)	32 (78.05)		126 (74.83)	32 (78.05)
III/IV	163 (17.30)	9 (21.95)		38 (23.17)	9 (21.85)
Comorbidities1			0.236			1.000
Present	417 (44.27)	22 (53.66)		88 (53.66)	22 (53.66)
Absent	525 (55.73)	19 (46.34)		76 (46.34)	19 (46.34)
Location			0.450			0.884
Gastric	650 (69.00)	26 (63.41)		106 (64.63)	26 (63.41)
Non-gastric	292 (31.00)	15 (36.58)		58 (35.37)	15 (36.58)
Chief complaint
Abdominal pain	303 (32.17)	15 (36.58)	0.554	54 (32.93)	15 (36.58)	0.657
Abdominal distention	149 (15.82)	9 (21.95)	0.295	23 (14.02)	9 (21.95)	0.211
Hematemesis	42 (4.46)	3 (7.32)	0.429	9 (5.49)	3 (7.32)	0.710
Hematochezia	167 (17.72)	9 (21.95)	0.490	34 (20.73)	9 (21.95)	0.864
Medical examination	275 (29.19)	11 (26.83)	0.744	42 (25.61)	11 (26.83)	0.906
Other	96 (10.19)	2 (4.88)	0.266	17 (10.37)	2 (4.88)	0.278

¹Comorbidities: comprised of hypertension, diabetes mellitus, anemia, pulmonary disease (asthma, pneumonia, chronic obstructive pulmonary disease, etc.), heart disease (arrhythmia, coronary atherosclerotic heart disease, etc.), liver disease (hepatitis, cirrhosis, etc.), renal disease (nephritis, chronic kidney disease, etc.) and central nervous system disease (cerebrovascular disease, neurodegenerative disease, etc.). Bold values indicate P < 0.05. ASA: American Society of Anesthesiologists; BMI: Body mass index; MGIST: Multiple gastrointestinal stromal tumors; SGIST: Solitary gastrointestinal stromal tumors.