Gut microbiome in acute pancreatitis: A review based on current literature

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2021; 27(30): 5019-5036
Published online Aug 14, 2021. doi: 10.3748/wjg.v27.i30.5019

Table 5 Altered microbiome composition in acute pancreatitis vs healthy controls

No.	Techniques used for microbiome profiling	Healthy control	Acute pancreatitis	Ref.
1	qPCR (Fecal samples)	Firmicutes↑	Firmicutes↓	[84]
		Bacteroidetes↓	Bacteroidetes↑
		Proteobacteria↓	Proteobacteria↑
		Actinobacteria↑	Actinobacteria↓
		Tenericutes↓	Tenericutes↑
2	16S rRNA gene sequencing (Fecal samples)	Proteobacteria↓	Bacteroidetes↓	[83]
			Proteobacteria↑
			Escherichia/Shigella↑
			Enterococcus↑
			Enterobacteriaceae↑
			Prevotella↓
			Faecalibacterium↓
			Bifidobacterium↓
3	16S rRNA gene sequencing (Fecal samples)	NA	Bacteroidetes↑	[85]
			Proteobacteria↑
			Firmicutes↓
			Actinobacteria↓
4	16S rRNA gene sequencing (Fecal samples)	NA	Enterobacteriaceae↑	[21]
			Enterococcus↑
			Bifidobacteria↓

NA: Not available. ↑: Higher level; ↓: Lower level.

Citation: Patel BK, Patel KH, Bhatia M, Iyer SG, Madhavan K, Moochhala SM. Gut microbiome in acute pancreatitis: A review based on current literature. World J Gastroenterol 2021; 27(30): 5019-5036
URL: https://www.wjgnet.com/1007-9327/full/v27/i30/5019.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i30.5019

Patel BK, Patel KH, Bhatia M, Iyer SG, Madhavan K, Moochhala SM. Gut microbiome in acute pancreatitis: A review based on current literature. World J Gastroenterol 2021; 27(30): 5019-5036 [PMID: 34497432 DOI: 10.3748/wjg.v27.i30.5019]

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