Gut microbiome in acute pancreatitis: A review based on current literature

Table 1 Revised Atlanta classification and determinant-based classification of acute pancreatitis

Revised Atlanta classification of disease severity
Mild AP	No organ failure
	No local or systemic complications
Moderately severe AP	Organ failure that resolved within 48 h (transient organ failure) and /or
	Local or systemic complications without persistent organ failure
Severe AP	Persistent organ failure > 48 h
	Single organ failure
	Multiple organ failure
A modified Marshal score defines a persistent organ failure
Determinant-based classification of disease severity
RACAP	DBCAPS
Mild AP	Mild AP
Absence of organ failure	Absence of organ failure
Absence of local complications	Absence of (peri-) pancreatic necrosis
Moderately severe AP	Moderate AP
Local complications and/or	Sterile (peri-) pancreatic necrosis and/or
Transient organ failure	Transient organ failure
Severe AP	Severe AP
Persistent organ failure	Persistent organ failure or
	Infected (peri-) pancreatic necrosis
	Critical AP persistent organ failure
	Infected (peri-) pancreatic necrosis

AP: Acute pancreatitis; DBCAPS: Determinant-based classification of acute pancreatitis severity; RACA: Revised Atlanta classification. Persistent organ failure is defined by a modified Marshal score or a sepsis-related organ failure assessment score.