Acute kidney injury and hepatorenal syndrome in cirrhosis

Table 2 The current and past consensus definitions of acute kidney injury in cirrhosis

Criteria	Stage	Definition
ADQI/ICA in 2010[19]		The absolute increase in serum Cr of at least 0.3 mg/dL or 1.5 × baseline serum creatinine
	Stage 1	Increase of 0.3 mg/dL within 48 h or 1.5-2 × baseline serum creatinine
	Stage 2	Increase of 2-3 × baseline serum Cr
	Stage 3	At least 3 × baseline serum Cr with an increase of 0.5 mg/dL or currently on RRT
ICA-AKI in 2015[14]		An absolute increase in serum Cr of at least 0.3 mg/dL within 48 h or 1.5 × baseline Cr level within the last 7 d
	Stage 1A	Increase of 0.3 mg/dL from baseline in 48 h, 1.5-2 × baseline serum creatine. Absolute value of serum Cr < 1.5 mg/dL
	Stage 1B	Increase of 0.3 mg/dL from baseline in 48 h, 1.5-2 × baseline serum creatine. Absolute value of serum Cr > 1.5 mg/dL
	Stage 2	Increase of 2-3 × baseline
	Stage 3	Greater than 3 × baseline Cr, Cr > 4 mg/dL with rise of > 0.5, or on RRT

RRT: Renal replacement therapy; ADQI: Acute Dialysis Quality Initiative; ICA: International Club of Ascites; AKI: Acute kidney injury; Cr: Creatinine.