Clinical indicators for progression of nonalcoholic steatohepatitis to cirrhosis

Table 2 Role of imaging techniques in clinical progression of nonalcoholic steatohepatitis

Sr. No.	Imaging modality	Ref.	Journal	Year	Results
1	Ultrasound	Sanyal[32]	Gastroenterology	2002	US is currently the preferred method in United States for screening asymptomatic patients with elevated liver enzymes and suspected NAFLD with sensitivity in detecting steatosis varying between 60%–94%
2	Magnetic Resonance Elastography	Iijima et al[35]	Hepatol Res	2007	Magnetic resonance elastography has excellent diagnostic accuracy with sensitivity and specificity of 98% and 99%, respectively, for detecting all grades of fibrosis
		Huwart et al[36]	Gastroenterology	2008	Magnetic resonance elastography was associated with a higher technical success rate than US elastography
3	Fibroscan	Wong et al[39]	Gut	2012	Transient elastography had shown good results in patients with NAFLD. It is a non-invasive method of assessing liver fibrosis which can be performed at the bedside or in the outpatient clinic
		Wong et al[40]	Hepatology	2010	Transient elastography had shown good results in patients with NAFLD. It is a non-invasive method of assessing liver fibrosis which can be performed at the bedside or in the outpatient clinic
		Ratziu et al[43]	Gastroenterology	2005	Fibroscan has now been validated in NAFLD, and represents a useful tool for rapid, non-invasive assessment of liver fibrosis and determining the need for biopsy. Nonetheless, fibroscan values should be interpreted in consonance with clinical, biological, and morphological data

US: Ultrasonography; NAFLD: Non-alcoholic fatty liver disease.