Apolipoprotein E polymorphism influences orthotopic liver transplantation outcomes in patients with hepatitis C virus-induced liver cirrhosis

doi:10.3748/wjg.v27.i11.1064

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2021; 27(11): 1064-1075
Published online Mar 21, 2021. doi: 10.3748/wjg.v27.i11.1064

Table 5 Logistic regression model predicting moderate and severe (A2A3) degree of liver inflammation

Variables	Odds ratio	95%CI	P value
Alcohol consumption	0.636	0.188-2.148	0.466
Gender–male	7.609	1.195-48.447	0.032^a
Mean MELD	0.932	0.829-1.049	0.244
Mean age	0.969	0.893-1.051	0.446
Mean BMI	0.874	0.782-0.976	0.017^a
APOE2	1.519	0.059-39.334	0.801
APOE3	2.850	0.121-66.917	0.516
APOE4	2.868	0.112-73.560	0.524

^aP < 0.05. MELD: Model for end-stage liver disease; BMI: Body mass index; APOE: Apolipoprotein E gene; CI: Confidence interval.

Citation: Nascimento JCR, Pereira LC, Rêgo JMC, Dias RP, Silva PGB, Sobrinho SAC, Coelho GR, Brasil IRC, Oliveira-Filho EF, Owen JS, Toniutto P, Oriá RB. Apolipoprotein E polymorphism influences orthotopic liver transplantation outcomes in patients with hepatitis C virus-induced liver cirrhosis. World J Gastroenterol 2021; 27(11): 1064-1075
URL: https://www.wjgnet.com/1007-9327/full/v27/i11/1064.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i11.1064