Prognostic value of the preoperative fibrinogen-to-albumin ratio in pancreatic ductal adenocarcinoma patients undergoing R0 resection

Figure 1 Receiver operating characteristics curve analysis based on preoperative fibrinogen concentration, albumin level, and fibrinogen-to-albumin ratio for overall survival. A: The area under the receiver operating characteristics curve (AUC) indicates the diagnostic power of preoperative plasma fibrinogen concentration. In this model, the optimum cut-off point for fibrinogen concentration was 3.31 g/L, AUC was 0.714 (95% confidence interval (CI): 0.649-0.779), with a sensitivity of 61.14% and a specificity of 79.37% by the Youden’s index; B: The AUC indicates the diagnostic power of preoperative plasma albumin level. In this model, the optimum cut-off point for albumin level was 45.2 g/L, AUC was 0.659 (95%CI: 0.580-0.738), with a sensitivity of 75.58% and a specificity of 53.85% by the Youden’s index; C: The AUC indicates the diagnostic power of preoperative fibrinogen-to-albumin ratio (FAR). In this model, the optimum cut-off point for FAR was 0.08, AUC was 0.743 (95%CI: 0.677-0.810), with a sensitivity of 59.91% and a specificity of 87.69% by the Youden’s index; D: By comparing AUC, the diagnostic power of FAR was the most powerful.