Altered metabolism of bile acids correlates with clinical parameters and the gut microbiota in patients with diarrhea-predominant irritable bowel syndrome

doi:10.3748/wjg.v26.i45.7153

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 26, Issue 45

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (8974)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-5) series, Tables (1-3) series.

Item

Count

PDF

527

WORD

227

HTML

4498

Figures (1-5)

258

Tables (1-3)

178

Sum=5688

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

335

Download

740

Sum=1075

Publishing Process of This Article

Item

Count

Browse

610

Download

1601

Sum=2211

Dec 7, 2020 (publication date) through Apr 26, 2024

Times Cited of This Article

Times Cited (44)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Gastroenterol. Dec 7, 2020; 26(45): 7153-7172
Published online Dec 7, 2020. doi: 10.3748/wjg.v26.i45.7153

Full Size Figure Download Figure

Figure 5 Correlations between fecal bile acids and microbiota composition in all subjects. The heatmap presents the Spearman correlation coefficients between unconjugated fecal bile acids and the distinguishing genera in all subject. Seven genera belong to the family Ruminococcaceae (Oscillibacter, Clostridium IV, Gemmiger, Anaerofilum, Anaerotruncus, Faecalibacterium, and Ruminococcus); one genus belongs to the family Rikenellaceae (Alistipes); two genera belong to the family Porphyromonadaceae (Odoribacter and Barnesiella); two genera belong to the family Lachnospiraceae (Coprococcus and Clostridium XlVb). All of the genera were decreased significantly in the IBS-D group except for Ruminococcus. ^aP < 0.05, ^bP < 0.01. CA: Cholic acid; CDCA: Chenodeoxycholic acid; DCA: Deoxycholic acid; LCA: Lithocholic acid; UDCA: Ursodeoxycholic acid.

Citation: Wei W, Wang HF, Zhang Y, Zhang YL, Niu BY, Yao SK. Altered metabolism of bile acids correlates with clinical parameters and the gut microbiota in patients with diarrhea-predominant irritable bowel syndrome. World J Gastroenterol 2020; 26(45): 7153-7172
URL: https://www.wjgnet.com/1007-9327/full/v26/i45/7153.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i45.7153